Laboratoire des Interactions Moléculaires et Réactivité Chimique et Photochimique
UMR 5623

Design and synthetic engineering of OMSs

Sustainable synthesis of elementary bricks and study of property / structure relationships that rule self-assembly phenomena.
 

This topic focuses on the design and the synthesis of organized molecular systems, based on functional organic molecules which are genuine building blocks that self-assemble on the mesoscopic scale.

All these systems constitute a library in which to pick up, to give tunable systems suitable for the chosen area of application. Having a strong emphasis on sustainable chemistry, the synthetic challenge will be to follow as many green chemistry principles as possible, e.g. molecular economy, the use of natural renewable resources, bio-based and bio-inspired molecules…


Examples of biosourced or bioinspired architectures, DNA, lipopeptide, and amphiphilic dendrimer derived from sugars

In order to control them, a better understanding of the driving forces of self-assembly is one of our main targets. The final aim is to establish structure / aggregation correlations, and therefore conceive tunable systems, which can be used in various applications.

Electron microscopy of vesicles obtained from sugar catanionic surfactants
 
In parallel to the standard physico-chemical studies that are usually run in aqueous medium, the self-assembly of our systems is also studied in non-conventional structured media. The objective is to understand and rationalize the formulation of these OMSs in these media.
Influence of the nature of the solvent on the self-assembly of ion-paired surfactants
 
 
>> Simple electron donor molecules based on triphenylamine and carbazole derivatives
Dyes Pigm., 2018, 153, 275-283
Bélières, M.; Sartor, V.; Fabre, P.-L.; Poteau, R.; Bordeau, G.; Chouini-Lalanne, N.
 
>> Influence of structural parameters on the self-association properties of anti-HIV catanionic dendrimers
ChemPhysChem, 2015, 16, 3433-3437
Pérez-Anes A. ; Rodrigues F. ; Caminade A.M. ; Stefaniu C. ; Tiersch B. ; Turrin C.O. ; Blanzat M
.
 
>> Influence of dermal formulation additives on the physicochemical characteristics of catanionic vesicles
Colloids Surf. A Physicochem Eng., 2018, 558, 373-383
Richard, C.; Souloumiac, E.; Jestin, J.; Blanzat, M.; Cassel, S.

 

2019 IMRCP