Laboratoire des Interactions Moléculaires et Réactivité Chimique et Photochimique
UMR 5623

Design and synthetic engineering of OMSs

Sustainable synthesis of elementary bricks and study of property / structure relationships that govern self-assembly phenomena.
 

This thematic is centered on the design and synthesis of organized molecular systems, based on functional organic molecules which are real building blocks that self-assemble on the mesoscopic scale.
All these systems constitute a library in which to pick up to give tunable systems suitable for the chosen area of application. With a strong emphasis on sustainable chemistry, the synthetic challenge will be to follow the principles of molecular economy, as well as to use natural renewable resources, and bio-based and bio-inspired molecules.

Examples of biosourced or bioinspired architectures, DNA, lipopeptide, and amphiphilic dendrimer derived from sugars

A better understanding of the driving forces of self-assembly -in order to control them- is one of our main targets. The final aim is to establish structure/aggregation correlations, and therefore to conceive tunable systems, which can be used for various applications.

Electron microscopy of vesicles obtained from sugar catanionic surfactants
 
In parallel to the standard physico-chemical studies that are usually run in aqueous medium, the self-assembly of our systems is also studied in non-conventional structured media. The objective is to understand and to rationalize the formulation of these OMSs in these media.
Influence of the nature of the solvent on the self-assembly of ion-paired surfactants
 
 
>> Synthesis, autoorganization and reactivity of amphiphilic derivatives of 1-aminoisoindole in water and formamide
J. Surfactants Deterg., 2014, 17, 101-109
Levkov I.V. ; Cassel S. ; Voitenko Z.V. ; Saffon N. ; Lattes A. ; Rico-Lattes I.
 
>> Influence of structural parameters on the self-association properties of anti-HIV catanionic dendrimers
ChemPhysChem, 2015, 16, 3433-3437
Pérez-Anes A. ; Rodrigues F. ; Caminade A.M. ; Stefaniu C. ; Tiersch B. ; Turrin C.O. ; Blanzat M
.
 
>> Cationic porphyrin–anionic surfactant mixtures for the promotion of self-organized 1:4 ion pairs in water with strong aggregation properties
ChemPhysChem, 2015, 16, 3877-3885
Pradines V. ; Bijani C. ; Stilgliani J.-L. ; Blanzat M. ; Rico-Lattes I. ; Pratviel G.

 

2018 IMRCP