Laboratoire des Interactions Moléculaires et Réactivité Chimique et Photochimique
UMR 5623

Polymeric nanomaterials

Temperature- or light-responsive polymers with controlled architectures (linear, branched or hyperbranched structures) are synthetized or chemically modified to get self-assemblies such as hydrogels, micelles, polymersomes, emulsions…
These assemblies have applications for drug delivery, photocatalytic water treatment or act as nanoreactors.
Two examples of this research are described below:

Organized supramolecular nanofibers obtained by wet-spinning

A single biocompatible small molecule, the N-heptyl-D-galactonamide has been spun into well-defined hydrogel filaments by wet-spinning. The counter-diffusion of water and dimethylsulfoxide triggers the self-assembly of the molecule resulting into radially.

Wet Spinning and Radial Self-Assembly of a Carbohydrate Low Molecular Weight Gelator into Well Organized Hydrogel Filaments
Chalard A.; Joseph P.; Souleille S.; Lonetti B.; Saffon-Merceron N.; Loubinoux I.; Vaysse L.; Malaquin L.; Fitremann J.
Nanoscale, 2019, Advanced article, https://doi.org/10.1039/C9NR02727K

 

Mechanistic insights into polyion complex associations

Polyionic complexes based on the association between poly(ethylene oxide-b- acrylix acid) block copolymers and a hyperbranched polymer, polylysine, were formed and characterized in a multi-technique approach, from light and X-ray scattering to Field Flow Fractionnation. The asset of each technique is discussed and proved to be essential.

Mechanistic insights into polyion complex associations
Gineste S.; Di Cola E.; Amouroux B.; Till U.; Marty J.-D.; Mingotaud A.-F.; Mingotaud C.; Violleau F.; Berti D.; Parigi G.; Luchinat C.; Balor S.; Sztucki M.; Lonetti B.

Macromolecules, 2018, 51, 1427-1440

2019 IMRCP