Laboratoire des Interactions Moléculaires et Réactivité Chimique et Photochimique
UMR 5623

Hybrid nanoparticles


Mixing inorganic nanoparticles or ions and soft matter (liquid crystal, polymer or surfactant) lead to new hybrid systems with combined properties and even synergies useful for material or biomedical applications. We also use up-converting nanoparticles for imaging purposes, photochromic nanomaterials for sensors, photocatalytic nanoparticles for environmental applications.
Two examples of this research are described below:

New colloidal Magnetic Resonance Imaging (MRI) contrast agents

Mixing double-hydrophilic block copolymers containing a poly(acrylic acid) block with gadolinium ions in water leads to the spontaneous formation of polymeric nanoparticles with high magnetic relaxivities that were successfully used for in vivo experiments as MRI contrast agents.

       ANR PRC-2019-2023
Assembly of double-hydrophilic block copolymers triggered by Gadolinium ions: new colloidal MRI contrast agents
Nano Lett., 2016, 16, 4069-4073
Frangville C. ; Li Y. ; Billotey C. ; Talham D.R. ; Taleb J. ; Roux P. ; Marty J.D. ; Mingotaud C.

Ionic Flash NanoPrecipitation (iFNP) for the facile, one-step synthesis of inorganic–organic hybrid nanoparticles in water
Nanoscale, 2017, 9, 1403-1408
Pinkerton N. M. ; Behar L. ; Hadri K. ; Amouroux B. ; Mingotaud C. ; Talham D. R. ; Chassaing S. ; Marty J.-D.


Microwave-assisted synthesis of upconverting nanoparticles

A simple change in the addition procedure of the inorganic reactants associated with careful control of the high-temperature heating reaction time enables the preparation of extremely small upconverting nanoparticles. We have described the first example of a trifluoroacetic acid-free, microwave-assisted synthesis of luminescent and homogeneous, pure hexagonal sub-5-nm Na(Gd−Yb)F4:Tm.

      PRCE ANR-15-CE09-0020

Importance of the mixing and high-temperature heating steps in the controlled thermal coprecipitation synthesis of sub-5-nm Na(Gd-Yb)F4:Tm
Amouroux B.; Roux C.; Marty J.-D.; Pasturel M.; Bouchet A.; Sliwa M.; Leroux O.; Gauffre F.; Coudret C.
Inorg. Chem., 2019, 58, 5082-5088

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