Laboratoire des Interactions Moléculaires et Réactivité Chimique et Photochimique
UMR 5623

Hybrid nanoparticles


Mixing inorganic nanoparticles or ions and soft matter (liquid crystal, polymer or surfactant) lead to new hybrid systems with combined properties and even synergies useful for material or biomedical applications. We also use up-converting nanoparticles for imaging purposes, photochromic nanomaterials for sensors, photocatalytic nanoparticles for environmental applications.
Two examples of this research are described below:

New colloidal Magnetic Resonance Imaging (MRI) contrast agents

Mixing double-hydrophilic block copolymers containing a poly(acrylic acid) block with gadolinium ions in water leads to the spontaneous formation of polymeric nanoparticles with high magnetic relaxivities that were successfully used for in vivo experiments as MRI contrast agents.

Assembly of double-hydrophilic block copolymers triggered by Gadolinium ions: new colloidal MRI contrast agents
Nano Lett., 2016, 16, 4069-4073
Frangville C. ; Li Y. ; Billotey C. ; Talham D.R. ; Taleb J. ; Roux P. ; Marty J.D. ; Mingotaud C.

Ionic Flash NanoPrecipitation (iFNP) for the facile, one-step synthesis of inorganic–organic hybrid nanoparticles in water
Nanoscale, 2017, 9, 1403-1408
Pinkerton N. M. ; Behar L. ; Hadri K. ; Amouroux B. ; Mingotaud C. ; Talham D. R. ; Chassaing S. ; Marty J.-D.


Synthesis of hybrid nanoparticles by flash nano-precipitation

A one step method based on flash nanoprecipitation enables the straightforward synthesis of nanoparticles by decoupling the formation of the inorganic core and surface functionalisation.

Quench ionic flash nano precipitation as a simple and tunable approach to decouple growth and functionalization for the one-step synthesis of functional LnPO4-based nanoparticles in water
Chem. Commun., 2018, 54, 9438-9441
Pinkerton N. M. ; Hadri K. ; Amouroux B. ; Behar L. ; Mingotaud C. ; Destarac M. ; Kulai I. ; Mazières S. ; Chassaing S. ; Marty J.-D.

2019 IMRCP